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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1511693Generated: November 4, 2026

Benzene, 1-fluoro-4-(trifluoromethyl)- → HCID 68426928, compound

https://huagongshe.com/reaction/1511693

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-fluoro-4-(trifluoromethyl)-HCID 67873—
Reactant7-Methyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-olHCID 68409696—
ProductHCID 68426928HCID 68426928—

Reaction Steps

The same method as in Example 1 was conducted using 7-methyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol (Reference Example 19) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 4-fluorobenzotrifluoride instead of 1-fluoronaphthalene to give the objective compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08217031B2
Source datasetuspto-grants-2012_07
ORD IDord-51484e8ccdd84bc8968261778caf6809
Source noteuspto-grants-2012_07