HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-fluoro-2-nitrobenzene → 4-(4-Chloro-3-nitrophenyloxy)-6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-fluoro-2-nitrobenzene | HCID 67659 | — |
| Reactant | 6-Methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol | HCID 13365156 | — |
| Product | 4-(4-Chloro-3-nitrophenyloxy)-6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine | HCID 68411508 | — |
Reaction Steps
The same method as in Example 1 was conducted using 6-methyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-4-ol (Reference Example 1) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2-chloro-5-fluoronitrobenzene instead of 1-fluoronaphthalene to give the objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217031B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-c0c5354e1d524cdbb799dd0462bed2c6 |
| Source note | uspto-grants-2012_07 |