Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1511701Generated: October 27, 2026

2-Fluoronaphthalene → 2,7-Dimethyl-4-(naphthalen-2-yloxy)-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine

https://huagongshe.com/reaction/1511701

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluoronaphthaleneHCID 67583—
Reactant2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-olHCID 68410119—
Product2,7-Dimethyl-4-(naphthalen-2-yloxy)-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepineHCID 68409927—

Reaction Steps

The same method as in Example 1 was conducted using 2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol (Reference Example 20) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2-fluoronaphthalene instead of 1-fluoronaphthalene to give the objective compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08217031B2
Source datasetuspto-grants-2012_07
ORD IDord-4350c3bd890348979aaae79f5c004fcc
Source noteuspto-grants-2012_07