HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoronaphthalene → 2,7-Dimethyl-4-(naphthalen-2-yloxy)-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoronaphthalene | HCID 67583 | — |
| Reactant | 2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol | HCID 68410119 | — |
| Product | 2,7-Dimethyl-4-(naphthalen-2-yloxy)-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine | HCID 68409927 | — |
Reaction Steps
The same method as in Example 1 was conducted using 2,7-dimethyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol (Reference Example 20) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2-fluoronaphthalene instead of 1-fluoronaphthalene to give the objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217031B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-4350c3bd890348979aaae79f5c004fcc |
| Source note | uspto-grants-2012_07 |