HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-chloro-3-fluorobenzene → 7-(3-Bromo-2-chlorophenyloxy)-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-chloro-3-fluorobenzene | HCID 3739301 | — |
| Reactant | 2-Methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol | HCID 68410459 | — |
| Product | 7-(3-Bromo-2-chlorophenyloxy)-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine | HCID 68410009 | — |
Reaction Steps
The same method as in Example 1 was conducted using 2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol (Reference Example 30) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3-bromo-2-chloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217031B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-165553eb323447e687cbd690f62afaa7 |
| Source note | uspto-grants-2012_07 |