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HRID 1511752作成日：2026年10月25日

1-Cyano-4-fluoronaphthalene → 7-(4-Cyanonaphthalen-1-yloxy)-5-ethyl-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine

https://huagongshe.com/reaction/1511752

反応式

関与物質

役割名称HCID仕込み量
反応物1-Cyano-4-fluoronaphthaleneHCID 2736734—
反応物5-Ethyl-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-olHCID 68412460—
生成物7-(4-Cyanonaphthalen-1-yloxy)-5-ethyl-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridineHCID 68409662—

反応手順

The same method as in Example 1 was conducted using 5-ethyl-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol (Reference Example 32) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 4-cyano-1-fluoronaphthalene instead of 1-fluoronaphthalene to give the objective compound.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08217031B2
出典データセットuspto-grants-2012_07
ORD IDord-5d184210c8a54d2eb5d987d988b4a169
出典メモuspto-grants-2012_07