1,2-Dichloro-4-fluorobenzene → 4-(3,4-Dichlorophenyloxy)-6-ethyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine

Participants

Reaction Steps

The same method as in Example 1 was conducted using 6-ethyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepin-4-ol (Reference Example 45) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3,4-dichloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.

Provenance & Evidence