4-Cbz-aminopiperidine → HCID 66953950, compound

HRID 1511801Notes

Reaction equation

HRID 1511801 reaction equation
Br[C:2]1[CH:3]=[CH:4][N:5]=[C:6]2[C:11]=1[N:10]=[C:9]([O:12][CH3:13])[CH:8]=[CH:7]2.[CH2:14]([O:21][C:22](=[O:30])[NH:23][CH:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH2:14]([O:21][C:22](=[O:30])[NH:23][CH:24]1[CH2:29][CH2:28][N:27]([C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[N:10]=3)[N:5]=[CH:4][CH:3]=2)[CH2:26][CH2:25]1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 15143044-Cbz-aminopiperidineHCID 534216178-Bromo-2-methoxy-1,5-naphthyridine

Product 1

HCID 66953950HCID 66953950, compound

Procedure

According to procedure F and starting from 8-bromo-2-methoxy-[1,5]naphthyridine and piperidin-4-yl-carbamic acid benzyl ester the title compound was isolated as a pale yellow foam (806 mg, 60%).

Sources & evidence

ORD record
ord-c7b9054984ee48e698e06e916bb59eb4
Source dataset
uspto-grants-2012_07
Patent number
US08217029B2

Reaction notes

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