Benzyl azetidin-3-ylcarbamate → HCID 66954107, compound

HRID 1511808Notes

Reaction equation

HRID 1511808 reaction equation
Br[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[C:5]([O:12][CH3:13])[CH:6]=[N:7]2.C(OC(=O)[NH:23][CH:24]1[CH2:27][NH:26][CH2:25]1)C1C=CC=CC=1>>[CH3:13][O:12][C:5]1[CH:6]=[N:7][C:8]2[C:3]([CH:4]=1)=[C:2]([N:26]1[CH2:27][CH:24]([NH2:23])[CH2:25]1)[CH:11]=[CH:10][CH:9]=2

Participants

3

Reactant 2

HCID 17750122Benzyl azetidin-3-ylcarbamateHCID 582278515-Bromo-3-methoxyquinoline

Product 1

HCID 66954107HCID 66954107, compound

Procedure

Starting from 5-bromo-3-methoxyquinoline (WO 2007/107965) and azetidin-3-yl-carbamic acid benzyl ester (commercial) the title compound was prepared according to procedure L followed by procedure G and was isolated as a pale yellow solid (122 mg, 63% over two steps).

Sources & evidence

ORD record
ord-cae7d5c0d0fb4d7e9c7777c8110a682e
Source dataset
uspto-grants-2012_07
Patent number
US08217029B2

Reaction notes

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