Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethyl methanetricarboxylate → 1-(3-Chloro-benzyl)-4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethyl methanetricarboxylate | HCID 80471 | — |
| 반응물 | (3-Chloro-benzyl)-pyrrol-1-yl-carbamic acid tert-butyl ester | HCID 67230403 | — |
| 생성물 | 1-(3-Chloro-benzyl)-4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid ethyl ester | HCID 67230491 | — |
반응 단계
Prepared according to the thermal cyclization condition used in Example 1 step c) from (3-chloro-benzyl)-pyrrol-1-yl-carbamic acid tert-butyl ester (1.0 eq.) and 2-ethoxycarbonyl-malonic acid diethyl ester (3.0 eq.). ESI (m/z): 347 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08217043B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-6e42462fd51844f7b55732054a817263 |
| 출처 메모 | uspto-grants-2012_07 |