Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Glycinate → {[1-(4-Trifluoromethyl-benzyl)-4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carbonyl]-amino}-acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Glycinate | HCID 4684308 | — |
| 반응물 | 1-(4-Trifluoromethyl-benzyl)-4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid ethyl ester | HCID 67230487 | — |
| 생성물 | {[1-(4-Trifluoromethyl-benzyl)-4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carbonyl]-amino}-acetic acid | HCID 54751143 | — |
반응 단계
Prepared according to the glycinolysis condition used in Example 1 step d) from 1-(4-trifluoromethyl-benzyl)-4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid ethyl ester (1.0 eq.) and sodium glycinate (15 eq.). ESI (m/z): 410 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08217043B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-aada29c20bfc48dabba26681494b0872 |
| 출처 메모 | uspto-grants-2012_07 |