HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl iodide → Butyl-pyrrol-1-yl-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl iodide | HCID 10962 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | tert-Butyl 1H-pyrrol-1-ylcarbamate | HCID 49760548 | — |
| Product | Butyl-pyrrol-1-yl-carbamic acid tert-butyl ester | HCID 67230193 | — |
Reaction Steps
Prepared according to the N-alkylation condition used in Example 1 step b) from starting materials pyrrol-1-yl-carbamic acid tert-butyl ester (1.0 eq.), 1-iodobutane (2.0 eq.) and sodium hydride (1.3 eq.). 1H NMR (CDCl3, δ in ppm): 6.60 (m, 2H), 6.10 (m, 2H), 3.64 (t, 2H, J=7.0 Hz), 1.42 (s, 9H), 1.55-1.26 (m, 4H), 0.92 (t, 3H, J=7.0 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217043B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-be8fa04170d94aed822e3e535315bd7d |
| Source note | uspto-grants-2012_07 |