Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl malonyl chloride → 1-[Biphenyl-4-ylmethyl-(2-methoxycarbonyl-acetyl)-amino]-4-chloro-1H-pyrrole-2-carboxylic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl malonyl chloride | HCID 123460 | — |
| 반응물 | 1-[(biphenyl-4-ylmethyl)-amino]-4-chloro-1H-pyrrole-2-carboxylic acid methyl ester | HCID 67231604 | — |
| 생성물 | 1-[Biphenyl-4-ylmethyl-(2-methoxycarbonyl-acetyl)-amino]-4-chloro-1H-pyrrole-2-carboxylic acid methyl ester | HCID 67230438 | — |
반응 단계
Prepared according to the acylation condition used in Example 2 step f) from 1-[(biphenyl-4-ylmethyl)-amino]-4-chloro-1H-pyrrole-2-carboxylic acid methyl ester and chlorocarbonyl-acetic acid methyl ester (1.5 eq.). ESI (m/z): 441 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08217043B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-1a1126293f634034ac2def0767f56897 |
| 출처 메모 | uspto-grants-2012_07 |