HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Trifluoromethyl)benzaldehyde → 4-Bromo-1-[(4-trifluoromethyl-benzylidene)-amino]-1H-pyrrole-2-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Trifluoromethyl)benzaldehyde | HCID 67996 | — |
| Reactant | Methyl 1-amino-4-bromo-1H-pyrrole-2-carboxylate | HCID 58423493 | — |
| Product | 4-Bromo-1-[(4-trifluoromethyl-benzylidene)-amino]-1H-pyrrole-2-carboxylic acid methyl ester | HCID 67232144 | — |
Reaction Steps
Prepared according to the imine formation condition used in Example 18 step b) from 1-amino-4-bromo-1H-pyrrole-2-carboxylic acid methyl ester and 4-trifluoromethylbenzaldehyde. 1H NMR (CDCl3, δ in ppm): 8.44 (s, 1H), 7.96 (d, 2H, J=7.8 Hz), 7.70 (d, 2H, J=7.8 Hz), 7.27 (d, 1H, J=1.8 Hz), 6.99 (d, 1H, J=1.6 Hz), 3.85 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217043B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-e09e78dc167f44aab69af72b6030674d |
| Source note | uspto-grants-2012_07 |