HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
L-Alanine → 2-(S)-[(6-Chloro-4-hydroxy-2-oxo-1-pyridin-3-ylmethyl-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carbonyl)-amino]-propionic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | L-Alanine | HCID 5950 | — |
| Edukt | Sodium Methoxide | HCID 10942334 | — |
| Edukt | 6-Chloro-4-hydroxy-2-oxo-1-pyridin-3-ylmethyl-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid methyl ester | HCID 67230778 | — |
| Produkt | 2-(S)-[(6-Chloro-4-hydroxy-2-oxo-1-pyridin-3-ylmethyl-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carbonyl)-amino]-propionic acid | HCID 54751169 | — |
Reaktionsschritte
Prepared according to the reaction condition used in Example 19 step a) from 6-chloro-4-hydroxy-2-oxo-1-pyridin-3-ylmethyl-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid methyl ester, L-alanine and NaOMe. ESI (m/z): 391 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08217043B2 |
| Quelldatensatz | uspto-grants-2012_07 |
| ORD ID | ord-052ec6481d2a4e27ab83e8d57ddde822 |
| Quellennotiz | uspto-grants-2012_07 |