反应详情

A mixture of 3.0 g of 6-(4-chlorophenyl)-pyridazinone, 50 ml of dry pyridine and 3.2 g of phosphorus pentasulfide was refluxed for 1 hour, evaporated to dryness and extracted with 200 ml of ether. The ether extract was washed with water (3×100 ml), brine (100 ml), dried over magnesium sulfate and evaporated to yield 3.0 g of 6-(4-chlorophenyl)-pyridazinthione as a yellow solid.

1. temperaturewas refluxed for 1 hour
2. customevaporated to dryness
3. extractionextracted with 200 ml of ether
4. extractionThe ether extract
5. washwas washed with water (3×100 ml), brine (100 ml)
6. dry with materialdried over magnesium sulfate
7. customevaporated