2-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline → HCID 67527994, compound

HRID 1512172Notes

Reaction equation

HRID 1512172 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8](B2OC(C)(C)C(C)(C)O2)[CH:7]=[CH:6][C:5]=1[NH2:19])([O-:3])=[O:2].Cl.Cl[C:22]1[CH:27]=[CH:26][N:25]=[C:24]([C:28]([F:31])([F:30])[F:29])[CH:23]=1>>[N+:1]([C:4]1[CH:9]=[C:8]([C:22]2[CH:27]=[CH:26][N:25]=[C:24]([C:28]([F:31])([F:30])[F:29])[CH:23]=2)[CH:7]=[CH:6][C:5]=1[NH2:19])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 162179142-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)anilineHCID 687703034-Chloro-2-(trifluoromethyl)pyridine hydrochloride

Product 1

HCID 67527994HCID 67527994, compound

Procedure

Following the procedure as described in Example 2, STEP A, the title compound was prepared from 2-nitro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine (0.300 g, 1.14 mmol, as prepared in the previous step) and 4-chloro-2-trifluoromethyl-pyridine hydrochloride (322 mg, 1.48 mmol) and was obtained as an orange solid.

Workup

  1. customwas obtained as an orange solid

Sources & evidence

ORD record
ord-84ea374aefcb4e99bb24181d6d2e9613
Source dataset
uspto-grants-2012_07
Patent number
US08217060B2

Reaction notes

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