反应详情

(E)-2-(2-Cyclohexyl-propenyl)-5-(2-trifluoromethyl-phenyl)-1H-benzimidazole was prepared from the acid chloride of 3-cyclohexyl-but-2-enoic acid (prepared as described in YOUNG, S. T. et al., “Synthetic Studies in the Fumagillin Series”, J. Org. Chem., 1963, pp 928-932, Vol. 28) and 3-nitro-2′-trifluoromethyl-biphenyl-4-ylamine (prepared as described in Example 3, STEP A) according to the procedures s described in Example 3, STEPS B, C and D.

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