HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloronicotinonitrile → HCID 68583512, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloronicotinonitrile | HCID 81079 | — |
| Reactant | 3-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride) | HCID 2734385 | — |
| Product | HCID 68583512 | HCID 68583512 | 91% |
Reaction Steps
Prepared in 91% yield from 2-chloro-3-cyanopyridine and 3-trifluoromethoxyphenylboronic acid according to the procedure described for Example 153A. MS (ESI−) m/z 264.9 (M+H)+; 1H NMR (CDCl3) δ 7.37-7.45 (m, 2H), 7.57 (dd, J=8.0, 8.0 Hz, 1H), 7.82 (br s, 1H), 7.91 (d, J=7.8 Hz, 1H), 8.11 (dd, J=7.8, 1.7 Hz, 1H), 8.90 (dd, J=4.7, 1.7 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217067B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-d09d9a661c624b0d83074ee9e6f7cba7 |
| Source note | uspto-grants-2012_07 |