2,3-Dichlorophenyl Isothiocyanate → 1-(2,3-Dichloro-phenyl)-3-[2-(4-chlorophenyl)-5-methyl-2H-pyrazol-3-ylmethyl]-thiourea

HRID 1512353ノート

反応式

HRID 1512353 の反応式
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[N:9]=[C:10]=[S:11].[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([N:19]2[C:23]([C:24]#[N:25])=[CH:22][C:21]([CH3:26])=[N:20]2)=[CH:15][CH:14]=1>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[NH:9][C:10]([NH:25][CH2:24][C:23]1[N:19]([C:16]2[CH:17]=[CH:18][C:13]([Cl:12])=[CH:14][CH:15]=2)[N:20]=[C:21]([CH3:26])[CH:22]=1)=[S:11]

参加物

3

反応物 2

HCID 27962812,3-Dichlorophenyl IsothiocyanateHCID 685833032-(4-chlorophenyl)-5-methyl-2H-pyrazole-3-carbonitrile

生成物 1

HCID 866035361-(2,3-Dichloro-phenyl)-3-[2-(4-chlorophenyl)-5-methyl-2H-pyrazol-3-ylmethyl]-thiourea収率 56%

実験手順

Prepared in 56% yield from 2,3-dichlorophenylisothiocyanate and the product of Example 205A according to the procedure described for Example 153B.

出典と根拠

ORDレコード
ord-245c1ede98574508aa832f95332034ed
出典データセット
uspto-grants-2012_07
特許番号
US08217067B2

反応ノート

読み込み中…