Dimethyl Sulfoxide → 4-chloro-2-fluoro-5-(2-pyrimidinyloxy)aniline
Reaction equation
[C:11](=[O:12])([O-:13])[O-:14].[CH3:24][S:25]([CH3:26])=[O:27].[CH3:28][CH2:29][C:30](=[O:31])[CH3:32].[Cl:17][c:18]1[n:19][cH:20][cH:21][cH:22][n:23]1.[K+:15].[K+:16].[NH2:1][c:2]1[c:3]([F:10])[cH:4][c:5]([Cl:9])[c:6]([OH:8])[cH:7]1>>[NH2:1][c:2]1[c:3]([F:10])[cH:4][c:5]([Cl:9])[c:6]([O:8][c:18]2[n:19][cH:20][cH:21][cH:22][n:23]2)[cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-30cccad19d47431ab95a89025c272dd4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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