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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1512368Generated: November 4, 2026

2-Fluorobenzonitrile → 2-[(1-Methylpiperidin-3-yl)oxy]benzonitrile

https://huagongshe.com/reaction/1512368

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-FluorobenzonitrileHCID 67855—
Reactant3-Piperidinol, 1-methyl-HCID 98016—
Product2-[(1-Methylpiperidin-3-yl)oxy]benzonitrileHCID 68583720—

Reaction Steps

2-Fluoro-benzonitrile was reacted with 1-methyl-piperidin-3-ol according to the method of Example 85A to provide the title compound. MS (DCI/NH3) m/z 217 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08217067B2
Source datasetuspto-grants-2012_07
ORD IDord-8207a5efd8904ddfabfd0a974f24d757
Source noteuspto-grants-2012_07