Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylate → HCID 66578219, compound

HRID 1512574Notes

Reaction equation

HRID 1512574 reaction equation
[CH3:1][O:2][C:3](=[O:19])/[CH:4]=[CH:5]/[C:6]1[C:7]([CH3:18])=[N:8][O:9][C:10]=1[C:11]1[CH:16]=[CH:15][C:14](Br)=[CH:13][CH:12]=1.[CH2:20]([O:22][C:23]([C:25]1([C:28]2[CH:33]=[CH:32][C:31](B3OC(C)(C)C(C)(C)O3)=[CH:30][CH:29]=2)[CH2:27][CH2:26]1)=[O:24])[CH3:21]>>[CH2:20]([O:22][C:23]([C:25]1([C:28]2[CH:33]=[CH:32][C:31]([C:14]3[CH:15]=[CH:16][C:11]([C:10]4[O:9][N:8]=[C:7]([CH3:18])[C:6]=4/[CH:5]=[CH:4]/[C:3]([O:2][CH3:1])=[O:19])=[CH:12][CH:13]=3)=[CH:30][CH:29]=2)[CH2:26][CH2:27]1)=[O:24])[CH3:21]

Participants

3

Reactant 2

HCID 53217182Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylateHCID 66577269HCID 66577269, compound

Product 1

HCID 66578219HCID 66578219, compound

Procedure

Prepared according to the procedure described in Example 3, Step 5, using (E)-3-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-acrylic acid methyl ester and 1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-cyclopropanecarboxylic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d86bc955e0f14b88b6051479bfde6824
Source dataset
uspto-grants-2012_07
Patent number
US08217066B2

Reaction notes

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