HuagongsheHuagongshe Chemistry Print Report · For research reference only
alpha-Bromo-o-chlorotoluene → 1-(4'-{4-[2-(2-Chloro-benzyloxy)-ethyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | alpha-Bromo-o-chlorotoluene | HCID 11905 | — |
| Reactant | 1-{4'-[4-(2-Hydroxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester | HCID 66577266 | — |
| Product | 1-(4'-{4-[2-(2-Chloro-benzyloxy)-ethyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-cyclopropanecarboxylic acid | HCID 51352435 | — |
Reaction Steps
Prepared according to the procedure described in Example 14, Step 4, using 1-{4′-[4-(2-hydroxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester and 1-bromomethyl-2-chloro-benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217066B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-9172a17194264570a07d579792dcf6e4 |
| Source note | uspto-grants-2012_07 |