HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 66577474, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | 3-bromo-3,3-difluoroprop-1-ene | HCID 555085 | — |
| Reactant | Indium | HCID 5359967 | — |
| Reactant | 5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde | HCID 82133792 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 66577474 | HCID 66577474 | — |
Reaction Steps
5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde (0.511 g, 1.92 mmol), 3-bromo-3,3-difluoro-propene (0.4977 g, 3.07 mmol), indium (0.357 g, 3.07 mmol) and sodium iodide (0.0142 g, 0.096 mmol) were combined in DMF (5 mL) and stirred at room temperature overnight. The reaction mixture was submitted to standard aqueous workup to afford the title compound, which was taken to the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217066B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-e6a8ad9c6ca8477a9e786cabf7114cf0 |
| Source note | uspto-grants-2012_07 |