HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodobenzene → 1-{4'-[4-((E)-1-Hydroxy-2,2-dimethyl-4-phenyl-but-3-enyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodobenzene | HCID 11575 | — |
| Reactant | 1-{4'-[4-(1-Hydroxy-2,2-dimethyl-but-3-enyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester | HCID 66577390 | — |
| Product | 1-{4'-[4-((E)-1-Hydroxy-2,2-dimethyl-4-phenyl-but-3-enyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester | HCID 66577392 | — |
Reaction Steps
Prepared according to the procedure described in Example 59, Step 1, using 1-{4′-[4-(1-hydroxy-2,2-dimethyl-but-3-enyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester and iodobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217066B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-3fe7769d6389473ebbcf52ef7682e4a9 |
| Source note | uspto-grants-2012_07 |