4-(4-Chlorophenyl)butan-2-one → HCID 66577356, compound
Reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH2:14])=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][CH2:23][C:24](=O)[CH3:25])=[CH:18][CH:17]=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH:14][CH:24]([CH3:25])[CH2:23][CH2:22][C:19]2[CH:18]=[CH:17][C:16]([Cl:15])=[CH:21][CH:20]=2)=[CH:6][CH:7]=1Participants
3
Procedure
Prepared according to the procedure described in Example 8, Step 1, using 5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine and 4-(4-chloro-phenyl)-butan-2-one.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-5702aab2bd7948178c8c596a08667d06
- Source dataset
- uspto-grants-2012_07
- Patent number
- US08217066B2
Reaction notes
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