5-(4-Bromophenyl)-3-methylisoxazol-4-amine → HCID 66577421, compound

HRID 1512658Notes

Reaction equation

HRID 1512658 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH2:14])=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:17]=1[CH2:23][CH2:24][C:25](=O)[CH3:26]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH:14][CH:25]([CH3:26])[CH2:24][CH2:23][C:17]2[C:18]([F:22])=[CH:19][CH:20]=[CH:21][C:16]=2[Cl:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 582185375-(4-Bromophenyl)-3-methylisoxazol-4-amineHCID 61495855HCID 61495855, compound

Product 1

HCID 66577421HCID 66577421, compound

Procedure

Prepared according to the procedure described in Example 8, Step 1, using 5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine and 4-(2-chloro-6-fluoro-phenyl)-butan-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ceb4f120e63a48758363d44d34be9903
Source dataset
uspto-grants-2012_07
Patent number
US08217066B2

Reaction notes

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