2-Pentanone, 4-methyl-4-phenyl- → [5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-(1,3-dimethyl-3-phenyl-butyl)-amine

HRID 1512682Notes

Reaction equation

HRID 1512682 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH2:14])=[CH:4][CH:3]=1.[CH3:15][C:16]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)([CH3:21])[CH2:17][C:18](=O)[CH3:19]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[C:9]=2[NH:14][CH:18]([CH3:19])[CH2:17][C:16]([CH3:21])([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH3:15])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 818982-Pentanone, 4-methyl-4-phenyl-HCID 582185375-(4-Bromophenyl)-3-methylisoxazol-4-amine

Product 1

HCID 66579181[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-(1,3-dimethyl-3-phenyl-butyl)-amine

Procedure

Prepared according to the procedure described in Example 8, Step 1, using 5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine and 4-methyl-4-phenyl-pentan-2-one.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b32a8966aba14a15803cd9cb5b0800d8
Source dataset
uspto-grants-2012_07
Patent number
US08217066B2

Reaction notes

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