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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1513499Generated: October 28, 2026

Carbamic acid, 4-pyridinyl-, phenyl ester → 1-{4-[4-(3,5-Dimethylmorpholin-4-yl)-6-{4-[(methylcarbamoyl)amino]phenyl}-1,3,5-triazin-2-yl]phenyl}-3-pyridin-4-ylurea

https://huagongshe.com/reaction/1513499

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCarbamic acid, 4-pyridinyl-, phenyl esterHCID 11401617—
Reactant1-(4-(4-(4-Aminophenyl)-6-(3,5-dimethyl morpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylureaHCID 67438018—
Product1-{4-[4-(3,5-Dimethylmorpholin-4-yl)-6-{4-[(methylcarbamoyl)amino]phenyl}-1,3,5-triazin-2-yl]phenyl}-3-pyridin-4-ylureaHCID 665856110.8%

Reaction Steps

The title compound was prepared by following the procedure of example 462 step 7 using 1-(4-(4-(4-aminophenyl)-6-(3,5-dimethylmorpholino)-1,3,5-triazin-2-yl)phenyl)-3-methylurea and phenyl pyridin-4-ylcarbamate. Yield 15 mg, 0.8% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08217036B2
Source datasetuspto-grants-2012_07
ORD IDord-97df25052dbf476aa382603c8e0e6247
Source noteuspto-grants-2012_07