HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol hexane → (S)-styrene oxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol hexane | HCID 21585144 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | (S)-styrene oxide | HCID 114946 | 69% |
Reaction Steps
Colorless oily substance, 69% yield, >99% ee (CHIRALCEL OD-H, hexane/iPrOH 99.9:0.1); [α]D23 +26.1° (c=0.48, CHCl3); 1H NMR (CDCl3): δ7.39-7.26 (m, 5H), 3.88-3.85 (dd, J=2.6, 4.0 Hz, 1H), 3.17-3.13 (dd, J=4.0, 5.6 Hz, 1H), 2.82-2.79 ppm (dd, J=2.6, 5.6 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217184B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-1aff6eb1d80d479ea5c70b3a6ad8b6ba |
| Source note | uspto-grants-2012_07 |