反应详情

温度

50 °C

40 ml of ethylene glycol and 8.4 g (0.1 mole) ethylene glycol monosodium salt are weighed into a 100 ml round bottom flask. The reaction mixture is heated to 50° C. with stirring and at this temperature, 12.2 g (0.1 mole) of chloroacetic acid N,N-dimethylamide are added dropwise in 1 hour. The reaction mixture is kept at the same temperature for further 1 hour and subsequently submitted to fractionated distillation. The first fraction (boiling temperature approx. 80° C., 260 Pa) comprises the solvent ethylene glycol. The boiling temperature of the product fraction is 130-135° C. (13 Pa). The purity of the product is higher than 98% as determined by gas chromatography.

1. additionare added dropwise in 1 hour
2. distillationdistillation
3. customis 130-135° C.