HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylene Glycol → 2-hydroxyethoxy-acetic acid N,N-dimethylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylene Glycol | HCID 174 | — |
| Reactant | Tetrabutylammonium Hydroxide | HCID 2723671 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-hydroxyethoxy-acetic acid N,N-dimethylamide | HCID 16752596 | 32.1% |
Reaction Steps
The process of Example 6 is carried out with the difference that instead of ethylene glycol, dioxane is used as solvent and that 1 g of tetrabutylammonium hydroxide are added to the reaction mixture. In this case, the yield is 4.73 g (32.1%) of the title compound having purity higher than 98% as determined by gas chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217200B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-464bd1f9da6446a799825b5a4367f1aa |
| Source note | uspto-grants-2012_07 |