HuagongsheHuagongshe Chemistry Print Report · For research reference only
(-)-Isopulegol → (-)-Menthol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (-)-Isopulegol | HCID 170833 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | (-)-Menthol | HCID 16666 | — |
Reaction Steps
By adding 0.45 g of Raney nickel to 283.8 g of the thus obtained 1-isopulegol, 10 hours of hydrogenation was carried out at 70° C. under a hydrogen pressure of 2.5 MPa. By carrying out filtration and distillation of the reaction solution, 273.5 g (1.75 mol, 71.24% e.e.) of 1-menthol was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217204B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-6a2790c2fc0f43289c1028732507553b |
| Source note | uspto-grants-2012_07 |