Methanol → HCID 86659544, compound

Participants

Reaction Conditions

Reaction Steps

Ester deprotection (Step C) The 2,6,-dicarboethoxy-3,7-diheneicosylthieno[3,2-b]thieno[2′,3′:4,5]thieno[2,3-d]thiophene (10 mmol) product of Example 10, is dissolved in tetrahydrofuran (THF) (280 mL) then methanol (40 mL) is added. Lithium hydroxide (40 mmol) is dissolved in water (10 mL) and added to the stirred methanol and THF solution. A condenser is fitted and the reaction mixture is heated in an oil bath at 90° C. for 16 hr. The THF and methanol are removed under reduced pressure. 60 ml, of methanol and 10 mL of conc. hydrochloric acid are added then stirred for 4 h. Next 50 mL of water is added and the solid is filtered off. The product is dried under vacuum to give the 3,7-diheneicosyl thieno[3,2-b]thieno[2′,3′:4,5]thieno[2,3-d]thiophene-2,6-dicarboxylic acid. 1H NMR (D8-THF) δ 0.89 (6H, t, J=6.9 Hz), 1.17-1.45 (72H, m), 1.68-1.85 (4H, m), and 3.18-3.28 (4H, m).

Provenance & Evidence