Hydrochloric Acid → HCID 67004845, compound

Participants

Reaction Steps

Using the procedure demonstrated in Example 10, react 1-(2-{4-[2-(2,3-difluoro-phenyl)-6-methoxy-naphthalen-1-yloxy]-phenoxy}-ethyl)-piperidine (622 mg, 1.27 mmol), 2M HCl in ether (1.3 mL, 2.6 mmol) and boron tribromide (0.60 mL, 6.4 mmol) to give 309 mg (48%) of the title compound: mass spectrum (ion spray) 476.4 (M−Cl).

Provenance & Evidence