Hydrochloric Acid → HCID 57505874, compound

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Reaction Steps

1,1-Dimethylethyl-7-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate (Preparation 43) (735 mg, 1.55 mmol) was dissolved in 4M HCl in dioxane and the solution stirred for 1 h. The title compound was filtered off as a white solid and dried in a vacuum oven (462 mg, 1.13 mmol). δH (d6DMSO, 400 MHz): 9.24 (2H, brs), 8.51 (1H, d), 8.40 (1H, dd), 7.95 (1H, d), 7.92 (1H, dd), 7.57 (1H, d), 7.45 (1H, d), 4.98 (1H, septet), 3.28-3.18 (8H, m), 1.39 (6H, d). MS (ES): C22H22N4O2 requires 374; found 375 [M+H]+.

Provenance & Evidence