HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[2-(4-Nitro-phenyl)-vinyl]-pyridine → 4-[2-(Pyridin-4-yl)ethyl]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[2-(4-Nitro-phenyl)-vinyl]-pyridine | HCID 307136 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-[2-(Pyridin-4-yl)ethyl]aniline | HCID 233288 | 100% |
Reaction Steps
To the EtOAc solution (30 mL) of 4-[2-(4-nitro-phenyl)-vinyl]-pyridine (160 mg, 0.71 mmol) was added palladium on carbon (0.1 g, 50% wet). The suspension was hydrogenated at 50 psi of hydrogen for 2 hours. The mixture was filtered over a celite pad. The filtrate was concentrate to give 4-(2-pyridin-4-yl-ethyl)-phenylamine as a yellow solid (140 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08222249B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-cf83183b20bf479f9265910aa6ebd255 |
| Source note | uspto-grants-2012_07 |