Cyclohexylamine → HCID 24825862, compound

HRID 1514350Notes

Reaction equation

HRID 1514350 reaction equation
Cl[C:2]1[N:11]=[C:10](Cl)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[CH:13]1([NH2:19])[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1.[NH:20]1[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:22]=[N:21]1>>[CH:13]1([NH:19][C:10]2[C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[N:3]=[C:2]([N:20]3[C:28]4[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=4)[CH:22]=[N:21]3)[N:11]=2)[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1

Participants

4

Reactant 3

HCID 7965CyclohexylamineHCID 92211H-IndazoleHCID 2528862,4-Dichloroquinazoline

Product 1

HCID 24825862HCID 24825862, compound

Procedure

Was prepared according to Method A from 2,4-dichloroquinazoline, cyclohexylamine and indazole. Mp=278.1-281.4° C. LC-ESI-HRMS of [M+H]+ shows 344.1879 Da. Calc. 344.18752 Da, dev. 1.1 ppm.

Workup

  1. customWas prepared

Sources & evidence

ORD record
ord-17502847125d4b96bcf8365dc6d411ce
Source dataset
uspto-grants-2012_07
Patent number
US08222262B2

Reaction notes

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