HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiomorpholine 1,1-dioxide → HCID 46929241, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiomorpholine 1,1-dioxide | HCID 6484228 | — |
| Reactant | HCID 66718228 | HCID 66718228 | — |
| Product | HCID 46929241 | HCID 46929241 | 63% |
Reaction Steps
As described in example 52g, 6-[3-butyl-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid (45 mg, 0.15 mmol) was converted, using thiomorpholine-1,1-dioxide instead of cyclobutylamine, to the title compound (39 mg, 63%) which was obtained as a light yellow oil. MS: m/e=424.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08222246B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-d21997f54c2b45f5831baaffbe30d249 |
| Source note | uspto-grants-2012_07 |