Toluene → HCID 87217357, compound

Participants

Reaction Steps

To a mixture of 2-(2,6-dimethylphenyl)-3H-benzoimidazole-5-carboxylic acid (8.0 g) in SOCl2 (30 mL) was added 5 drops of DMF. After the suspension was stirred for 18 h, toluene (20 mL) was added and mixture was stirred for an additional 1 h. The suspension was filtered, washed with toluene and CH2Cl2. The white solid was dried under reduced pressure give 2-(2,6-dimethyl-phenyl)-3H-benzoimidazole-5-carbonyl chloride HCl salt; MS (ESI)m/z 267 (M+H).

Provenance & Evidence