反应详情

To a stirred solution of (2,4,6-trichlorophenyl)-methanol (350 mg, 1.67 mmol) in CH2Cl2 (10 mL) was added Dess-Martin reagent (742 mg, 1.75 mmol). After the addition, the solution was stirred at ambient temperature for 2 h. The reaction was quenched with sat. NaHCO3 and the aqueous layer was extracted with EtOAc. The organic layer was washed with water, brine, dried with MgSO4, and filtered. The solvent was removed under reduced pressure to give 2,4,6-trichlorobenzaldehyde as a white solid.

1. additionAfter the addition
2. customThe reaction was quenched with sat. NaHCO3
3. extractionthe aqueous layer was extracted with EtOAc
4. washThe organic layer was washed with water, brine
5. dry with materialdried with MgSO4
6. filtrationfiltered
7. customThe solvent was removed under reduced pressure