2-Aminoquinoline → 2-(2,6-Dimethylphenyl)-1H-indole-6-carboxylic acid quinolin-2-ylamide

Participants

Reaction Steps

The title compound was prepared from methyl 2-(2,6-dimethylphenyl)-1H-indole-6-carboxylate and 2-aminoquinoline analogous to Example 3-6. 1H NMR (DMSO-d6, 400 MHz) δ 11.60 (s, 1H), 11.01 (s, 1H), 8.40 (s, 2H), 7.95 (d, J=7.83 Hz, 1H), 7.89 (d, J=8.46 Hz, 1H), 7.80 (d, J=9.60 Hz, 1H), 7.74 (t, 1H), 7.65 (d, J=8.34 Hz, 1H), 7.52 (t, 1H), 7.28 (m, 1H), 7.19 (d, J=7.45 Hz, 1H), 6.44 (s, 1H), 2.15 (s, 6H). MS (m/z) 392.2 (M+1).

Provenance & Evidence