(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid → (R)-2-Amino-3-(4-methoxy-benzylsulfanyl)propionic acid methyl ester

HRID 1515241Notes

Reaction equation

HRID 1515241 reaction equation
[C:1]([C@@:8]([NH2:23])([CH2:12][S:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1)C(O)=O)([O:3][C:4](C)(C)C)=[O:2]>CO>[CH3:4][O:3][C:1](=[O:2])[C@@H:8]([NH2:23])[CH2:12][S:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=1

Participants

3

Reactant 1

HCID 68486000(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid

Product 1

HCID 14390800(R)-2-Amino-3-(4-methoxy-benzylsulfanyl)propionic acid methyl ester

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

(R)-2-BOC-amino-3-(4-methoxy-benzylsulfanyl)-propionic acid prepared in Step B of Preparation 27 and methanol were reacted according to the same procedure as Preparation 30 to give the title compound.

Workup

  1. customwere reacted
  2. customaccording to the same procedure as Preparation 30

Sources & evidence

ORD record
ord-b928fc50139f497da30949293488d921
Source dataset
uspto-grants-2012_07
Patent number
US08222414B2

Reaction notes

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