HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrazole → HCID 59542939, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrazole | HCID 1048 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 2,2-Dimethyl-propionic acid [(R)-2-(5-chloromethyl-7-nitro-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]methyl ester | HCID 59542988 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 59542939 | HCID 59542939 | — |
Reaction Steps
2,2-Dimethyl-propionic acid [(R)-2-(5-chloromethyl-7-nitro-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]methyl ester prepared in Preparation 41 and pyrazole were reacted according to the same procedure as Preparation 92 except that DMF was used as the solvent instead of DMSO to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08222414B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-06c24f1cfd524a3da21ede59e5a63bee |
| Source note | uspto-grants-2012_07 |