HuagongsheHuagongshe Chemistry Print Report · For research reference only
[(7-Cyclopentylamino-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]acetic acid → Cyclopentyl-{2-[(R)-4-(3-piperidin-1-yl-[1,2,4]oxadiazol-5-ylmethyl)-4,5-dihydro-thiazol-2-yl]-1H-indol-7-yl}-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [(7-Cyclopentylamino-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]acetic acid | HCID 66974336 | — |
| Reactant | HCID 178513428 | HCID 178513428 | — |
| Product | Cyclopentyl-{2-[(R)-4-(3-piperidin-1-yl-[1,2,4]oxadiazol-5-ylmethyl)-4,5-dihydro-thiazol-2-yl]-1H-indol-7-yl}-amine | HCID 59543033 | — |
Reaction Steps
[(7-Cyclopentylamino-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]acetic acid prepared in Example 75 and N-hydroxypiperidinecarboxamidine were reacted according to the same procedure as Example 262 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08222414B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-4cdb3f0ead3549199715b3a15e5f3dd6 |
| Source note | uspto-grants-2012_07 |