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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1515322Generated: November 4, 2026

4-(Chloromethyl)quinoline--hydrogen chloride (1/1) → 4-(5-Methyl-4-nitro-benzoimidazol-1-ylmethyl)-quinoline

https://huagongshe.com/reaction/1515322

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)quinoline--hydrogen chloride (1/1)HCID 23001619—
Reactant5-Methyl-4-nitro-1-(pyridin-4-yl)methyl-1H-benzimidazoleHCID 59428635—
Product4-(5-Methyl-4-nitro-benzoimidazol-1-ylmethyl)-quinolineHCID 59428632—

Reaction Steps

Compound 5a was synthesized in the same manner as compound 2c using 4-chloromethylquinoline hydrochloride instead of 4-chloromethylpyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08222421B2
Source datasetuspto-grants-2012_07
ORD IDord-8bd5e05e81a642fcb11a8cb10e5d613f
Source noteuspto-grants-2012_07