2-Nitro-4-(trifluoromethyl)phenol → 2-Amino-4-(trifluoromethyl)phenol

Participants

Reaction Steps

To a solution of 4-hydroxy-3-nitrobenzotrifluoride (1.00 g) in tetrahydrofuran (20 ml), 10% palladium on activated carbon (100 mg) was added and stirred overnight under a hydrogen atmosphere at room temperature. After the reaction mixture was filtered through celite, the solvent was distilled off under reduced pressure to give 2-amino-4-(trifluoromethyl)phenol (780 mg) as a gray powder.

Provenance & Evidence