Sodium Iodide → HCID 178503134, compound

Participants

Reaction Steps

0.48 g of methanesulfonyl chloride was added to 20 ml of methylene chloride solution including 0.4 g of (E)-5-hydroxy-N-phenyl-2-(phenylthiomethylene) pentanethioamide, 0.46 g of triethylamine and 0.69 of sodium iodide. The resulting solution was stirred at room temperature for 3 hours, and added with water, extracted with ethyl acetate. The organic layer was washed with brine, dried with anhydrous magnesium sulfate, filtered, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to obtain 0.23 g of the title compound.

Provenance & Evidence