2-Morpholinoethanol → HCID 66850566, compound

HRID 1515488Notes

Reaction equation

[OH:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1.CN(C)CCO[C:15]1[CH:20]=[C:19]([B:21]([OH:23])[OH:22])[CH:18]=[CH:17][N:16]=1>>[N:4]1([CH2:3][CH2:2][O:1][C:15]2[CH:20]=[C:19]([B:21]([OH:23])[OH:22])[CH:18]=[CH:17][N:16]=2)[CH2:9][CH2:8][O:7][CH2:6][CH2:5]1

Participants

Reactant 2

HCID 611632-Morpholinoethanol

HCID 66850324HCID 66850324, compound

Product 1

HCID 66850566HCID 66850566, compound

Procedure

[2-(2-Morpholin-4-yl-ethoxy)-4-pyridinyl]-boronic acid is prepared from N-(2-hydroxyethyl)-morpholine according to the procedure described for the preparation of [2-(2-dimethylamino-ethoxy)-4-pyridinyl]-boronic acid. MS (m/z): 253 (M+1).

Sources & evidence

ORD record: ord-f7cdf450f8cb43ffa81e309fa6bbfad4
Source dataset: uspto-grants-2012_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08222424B2

Reaction notes

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