2-(5-Carbamoyl-2-fluorophenylamino)-2-(4-fluoro-3-methoxyphenyl)acetic acid → HCID 24880757, compound

Participants

Reaction Steps

Example 81 was prepared according to the general coupling condition using 27A and 76P. 1H NMR (400 MHz, Methanol-d4) δ ppm 0.92-1.09 (m, 2H) 1.08-1.19 (m, 1H) 1.19-1.28 (m, 3H) 1.33-1.48 (m, 1H) 2.18-2.51 (m, 2H) 2.89 (dd, J=5.31, 2.27 Hz, 1H) 3.03-3.19 (m, 1H) 3.64-3.76 (m, 6H) 3.79-3.96 (m, 1H) 4.00-4.27 (m, 3H) 5.44 (s, 1H) 6.18 (d, J=2.02 Hz, 1H) 6.93-7.22 (m, 7 H) 7.27 (dd, J=8.21, 2.15 Hz, 1H) 7.66-7.75 (m, 1H) 9.48 (s, 1H), LC-MS 715 (M+H).

Provenance & Evidence